Stadium: SNU Stadium Round: 1
| NCAAF | 2022/10/08 19:00 | Southern Nazarene v Harding Bisons | L | 28-56 |
| NCAAF | 2021/10/09 19:00 | Harding Bisons v Southern Nazarene | L | 49-10 |
| NCAAF | 2019/10/05 23:00 | Harding Bisons v Southern Nazarene | L | 31-3 |
| NCAAF | 2018/09/15 18:00 | Southern Nazarene v Harding Bisons | L | 0-42 |
| NCAAF | 2022/11/13 00:00 | Oklahoma Baptist Bison v Southern Nazarene | W | 21-56 |
| NCAAF | 2022/11/05 19:00 | Southern Arkansas Muleriders v Southern Nazarene | W | 44-49 |
| NCAAF | 2022/10/29 19:00 | Southern Nazarene v Henderson State Reddies | L | 41-42 |
| NCAAF | 2022/10/22 20:00 | Southern Nazarene v Northwestern Oklahoma State Rangers | W | 27-21 |
| NCAAF | 2022/10/15 22:30 | Southwestern Oklahoma State Bulldogs v Southern Nazarene | W | 38-45 |
| NCAAF | 2022/10/08 19:00 | Southern Nazarene v Harding Bisons | L | 28-56 |
| NCAAF | 2022/10/01 19:00 | Arkansas Tech Wonder Boys v Southern Nazarene | L | 48-35 |
| NCAAF | 2022/09/24 23:00 | Southeastern Oklahoma State Savage Storm v Southern Nazarene | W | 34-45 |
| NCAAF | 2022/11/12 20:00 | Harding Bisons v Arkansas Tech Wonder Boys | W | 55-10 |
| NCAAF | 2022/11/05 19:00 | Southwestern Oklahoma State Bulldogs v Harding Bisons | W | 29-37 |
| NCAAF | 2022/10/29 20:00 | Harding Bisons v Northwestern Oklahoma State Rangers | W | 28-7 |
| NCAAF | 2022/10/22 19:00 | Arkansas Monticello Boll Weevils v Harding Bisons | W | 43-56 |
| NCAAF | 2022/10/15 19:00 | Harding Bisons v Henderson State Reddies | L | 14-15 |
| NCAAF | 2022/10/08 19:00 | Southern Nazarene v Harding Bisons | W | 28-56 |
| NCAAF | 2022/10/01 19:00 | Harding Bisons v Oklahoma Baptist Bison | W | 38-23 |
| NCAAF | 2022/09/24 23:00 | Ouachita Baptist Tigers v Harding Bisons | L | 21-13 |