Stadium: George Gervin GameAbove Center
Home Manager: Stan Heath Away Manager: Bryan Smothers
| NCAAB | 2021/11/20 20:00 | Wayne St v Hillsdale Chargers | L | 62-68 |
| NCAAB | 2021/02/27 19:00 | Wayne St v Ferris State | W | 70-68 |
| NCAAB | 2021/02/26 23:00 | Wayne St v Ferris State | L | 71-84 |
| NCAAB | 2021/02/20 19:00 | Wayne St v Saginaw Valley | W | 86-67 |
| NCAAB | 2021/02/19 23:00 | Wayne St v Saginaw Valley | W | 80-65 |
| NCAAB | 2021/02/16 21:00 | Ashland v Wayne St | W | 60-64 |
| NCAAB | 2021/02/13 21:00 | Wisconsin-Parkside v Wayne St | W | 60-63 |
| NCAAB | 2021/02/12 21:00 | Wisconsin-Parkside v Wayne St | L | 68-64 |
| NCAAB | 2022/03/05 00:00 | Eastern Michigan v Miami Ohio | L | 63-76 |
| NCAAB | 2022/03/02 00:00 | Western Michigan v Eastern Michigan | L | 71-60 |
| NCAAB | 2022/02/26 20:30 | Eastern Michigan v Ball State | L | 64-75 |
| NCAAB | 2022/02/23 00:00 | Northern Illinois v Eastern Michigan | W | 72-74 |
| NCAAB | 2022/02/19 20:00 | Akron v Eastern Michigan | L | 67-48 |
| NCAAB | 2022/02/17 17:00 | Buffalo v Eastern Michigan | L | 83-69 |
| NCAAB | 2022/02/16 00:00 | Eastern Michigan v Central Michigan | W | 75-70 |
| NCAAB | 2022/02/12 20:30 | Ohio v Eastern Michigan | L | 74-56 |