| Colombia - Regional League | 2021/10/01 17:00 | FC Leones reserver v Estudiantes de Medellin | L | 2-0 |
| Colombia - Regional League | 2022/05/24 15:00 | Medellin City FC v Estudiantes de Medellin | L | 5-2 |
| Colombia - Regional League | 2022/05/09 14:00 | Lula FC v Estudiantes de Medellin | W | 2-3 |
| Colombia - Regional League | 2022/04/11 16:00 | Estudiantes de Medellin v Real Santuario | D | 1-1 |
| Colombia - Regional League | 2022/04/04 15:10 | Club Deportivo La Chalaca v Estudiantes de Medellin | L | 3-1 |
| Colombia - Regional League | 2022/02/28 16:00 | Sellos Colombianos v Estudiantes de Medellin | L | 6-3 |
| Colombia - Regional League | 2021/11/27 21:30 | CFD La Nororiental v Estudiantes de Medellin | D | 0-0 |
| Colombia - Regional League | 2021/11/16 17:00 | Estudiantes de Medellin v Molino Veijo | L | 1-2 |
| Colombia - Regional League | 2021/11/14 21:12 | Estudiantes de Medellin v CD Gallegol | W | 1-0 |
| Colombia - Regional League | 2022/05/24 15:00 | FC Leones reserver v Atletico Nacional Medellin reserver | W | 2-1 |
| Colombia - Regional League | 2022/05/17 13:00 | Envigado FC reserver v FC Leones reserver | L | 4-0 |
| Colombia - Regional League | 2022/04/23 17:18 | Real Santuario v FC Leones reserver | D | 2-2 |
| Colombia - Regional League | 2022/04/08 15:12 | FC Leones reserver v Universidad de Antioquia | W | 3-2 |
| Colombia - Regional League | 2022/02/28 16:29 | Molino Veijo v FC Leones reserver | L | 2-0 |
| Colombia - Regional League | 2021/11/29 16:00 | Independiente Sabaneta v FC Leones reserver | W | 4-5 |
| Colombia - Regional League | 2021/10/01 17:00 | FC Leones reserver v Estudiantes de Medellin | W | 2-0 |
| Colombia - Regional League | 2021/09/04 23:00 | FC Leones reserver v Molino Veijo | W | 2-0 |