Round: 7
| NCAAF | 2021/11/13 20:00 | Arkansas Tech Wonder Boys v Harding Bisons | W | 0-31 |
| NCAAF | 2021/11/06 19:00 | Southwestern Oklahoma State Bulldogs v Harding Bisons | W | 7-55 |
| NCAAF | 2021/10/30 19:00 | Northwestern Oklahoma State Rangers v Harding Bisons | W | 14-73 |
| NCAAF | 2021/10/23 20:00 | Harding Bisons v Arkansas Monticello Boll Weevils | W | 64-7 |
| NCAAF | 2021/10/16 19:00 | Henderson State Reddies v Harding Bisons | W | 21-46 |
| NCAAF | 2021/10/09 19:00 | Harding Bisons v Southern Nazarene | W | 49-10 |
| NCAAF | 2021/10/02 19:00 | Oklahoma Baptist Bison v Harding Bisons | W | 7-31 |
| NCAAF | 2021/09/25 23:00 | Harding Bisons v Ouachita Baptist Tigers | W | 38-21 |
| NCAAF | 2021/11/13 19:00 | Washburn Ichabods Football v Missouri Southern Lions | W | 38-28 |
| NCAAF | 2021/11/06 18:00 | Pittsburgh State Gorillas v Washburn Ichabods Football | W | 26-28 |
| NCAAF | 2021/10/30 18:00 | Washburn Ichabods Football v Northeastern State Riverhawks | W | 35-0 |
| NCAAF | 2021/10/23 19:00 | Central Oklahoma v Washburn Ichabods Football | W | 17-29 |
| NCAAF | 2021/10/16 18:00 | Washburn Ichabods Football v NW Missouri State | W | 17-16 |
| NCAAF | 2021/10/09 18:00 | Washburn Ichabods Football v Fort Hays State University Tigers | W | 23-20 |
| NCAAF | 2021/10/02 18:00 | Emporia State v Washburn Ichabods Football | L | 35-30 |
| NCAAF | 2021/09/25 18:00 | Washburn Ichabods Football v Missouri Western Griffons | W | 47-41 |