[58] John Millman 5-7,6-7 Karen Khachanov [31] 2021-10-22 15:30
Stadium: Central Court Round: 27 Ground: Hardcourt indoor
Head to Head
| ATP Auckland | 2020/01/15 08:20 | Karen Khachanov v John Millman | 6-4,3-6,3-6 |
Home History
| ATP Moskva | 2021/10/20 13:25 | Illya Marchenko v John Millman | 1-6,7-5,4-6 |
| ATP Moskva | 2021/10/18 12:10 | John Millman v Benjamin Bonzi | 6-7,6-4,6-3 |
| ATP Indian Wells | 2021/10/10 18:00 | John Millman v Jannik Sinner | 2-6,2-6 |
| ATP Indian Wells | 2021/10/09 01:00 | Jack Sock v John Millman | 5-7,6-4,3-6 |
| ATP Sofia | 2021/10/01 11:00 | John Millman v Marcos Giron | 4-6,2-6 |
| ATP Sofia | 2021/09/30 09:00 | John Millman v Illya Marchenko | 5-7,7-6,6-3 |
| ATP Sofia | 2021/09/28 09:00 | John Millman v Mikael Ymer | 6-2,6-4 |
| ATP Nur-Sultan | 2021/09/24 09:10 | James Duckworth v John Millman | 6-4,6-4 |
Away History
| ATP Moskva | 2021/10/20 18:10 | James Duckworth v Karen Khachanov | 6-3,3-6,1-6 |
| ATP Indian Wells | 2021/10/13 21:25 | Nikoloz Basilashvili v Karen Khachanov | 6-4,7-6 |
| ATP Indian Wells | 2021/10/12 19:40 | Karen Khachanov v Pablo Carreno Busta | 6-0,6-4 |
| ATP Indian Wells | 2021/10/11 01:00 | Karen Khachanov v Emil Ruusuvuori | 6-2,7-5 |
| ATP Metz | 2021/09/23 12:00 | Peter Gojowczyk v Karen Khachanov | 6-3,7-6 |
| ATP Metz | 2021/09/21 11:30 | Alexandre Muller v Karen Khachanov | 6-4,1-6,3-6 |
| US Open | 2021/08/31 15:00 | Karen Khachanov v Lloyd Harris | 4-6,6-1,6-4,3-6,2-6 |
| ATP Cincinnati | 2021/08/18 14:00 | Karen Khachanov v Felix Auger Aliassime | 7-6,3-6,4-6 |