[46] Texas Tech 21-52 Oklahoma [3] 2021-10-30 19:30
Stadium: Gaylord Family Oklahoma Memorial Stadium Round: 1
Home Manager: Lincoln Riley Away Manager: Matt Wells
Head to Head
| NCAAF | 2020/11/01 00:00 | Oklahoma v Texas Tech | L | 62-28 |
| NCAAF | 2019/09/28 16:00 | Texas Tech v Oklahoma | L | 16-55 |
| NCAAF | 2018/11/04 00:00 | Oklahoma v Texas Tech | L | 51-46 |
| NCAAF | 2017/10/29 00:00 | Texas Tech v Oklahoma | L | 27-49 |
| NCAAF | 2016/10/23 00:00 | Oklahoma v Texas Tech | L | 66-59 |
| NCAAF | 2015/10/24 19:30 | Oklahoma v Texas Tech | L | 63-27 |
| NCAAF | 2014/11/15 20:30 | Texas Tech v Oklahoma | L | 30-42 |
| NCAAF | 2012/10/06 12:00 | Texas Tech v Oklahoma | L | 20-41 |
Home History
| NCAAF | 2021/10/23 16:00 | Kansas State v Texas Tech | L | 25-24 |
| NCAAF | 2021/10/16 20:00 | Texas Tech v Kansas | W | 41-14 |
| NCAAF | 2021/10/09 23:00 | TCU v Texas Tech | L | 52-31 |
| NCAAF | 2021/10/02 19:30 | Texas Tech v West Virginia | W | 23-20 |
| NCAAF | 2021/09/25 16:00 | Texas Tech v Texas | L | 35-70 |
| NCAAF | 2021/09/18 23:00 | Florida Intl v Texas Tech | W | 21-54 |
| NCAAF | 2021/09/11 23:00 | Stephen F. Austin v Texas Tech | W | 22-28 |
| NCAAF | 2021/09/04 23:00 | Texas Tech v Houston | W | 38-21 |
Away History
| NCAAF | 2021/10/23 16:00 | Oklahoma v Kansas | W | 35-23 |
| NCAAF | 2021/10/16 23:30 | TCU v Oklahoma | W | 31-52 |
| NCAAF | 2021/10/09 16:00 | Oklahoma v Texas | W | 55-48 |
| NCAAF | 2021/10/02 19:30 | Oklahoma v Kansas State | W | 37-31 |
| NCAAF | 2021/09/25 23:30 | West Virginia v Oklahoma | W | 13-16 |
| NCAAF | 2021/09/18 16:00 | Nebraska v Oklahoma | W | 16-23 |
| NCAAF | 2021/09/11 23:00 | Western Carolina v Oklahoma | W | 0-76 |
| NCAAF | 2020/12/31 01:00 | Florida v Oklahoma | W | 20-55 |